3. Fifth Avenue, East 90th Street-East 105th Street (Miles 23-24)

Image via TCS NYC Marathon website

You most likely won’t be visiting any museums during the marathon, but this leg of the race will take runners through the Museum Mile, situated on the east side of Central Park. As participants race down Fifth Avenue, they’ll pass some of New York City’s most famous institutions, including the Guggenheim Museum, the Jewish Museum, the National Academy Museum, El Museo del Barrio, and the Museum of the City of New York.